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    Progress in drug researchfortschritte der arzneimittelforschungprogrès des recherches pharmaceutiques high resolution nuclear magnetic resonance spectroscopy of biological samples as an aid to drug development volume 31 of progress in drug research contains 13 articles, a sub ject index, an index for all articles that have been published so far in this series of monographs, as well as an author and subject index for all 31 volumes. This up-to-date and evidence-based reference closes several identified knowledge gaps concerning medications eliminated by the kidneys. The reviews in this volume are particularly concerned with the therapy of helminth diseases, with pyramidinones as biody namic agents, and with quinolones which are of interest in the treat ment of infections. Researchers who are actively engaged in the same or in similar fields of research are sure to benefit from these efforts. The pharmacology of caffeine is re viewed from the viewpoint of its role in combination with other phy siologically active substances, and the chapter on high resolution nuc lear magnetic resonance spectroscopy demonstrates the importance of this method in the development of new drugs.

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